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Figure 4 | Breast Cancer Research

Figure 4

From: Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence

Figure 4

Elafin-positive tumor cells are prognostic of poor RFS in luminal A-like (ER+/PR+/Ki67 low) breast cancer. (A) The proportion of tumors positive (elafin score > 0) and negative (elafin score = 0) for elafin-positive cells, separated by breast cancer subtype. Statistical significance determined by Fisher’s exact test. (B) Patients were separated by breast cancer subtype, luminal A-like, luminal B, triple receptor-negative breast cancer (TNBC), and human epidermal growth factor receptor 2 (HER2)-postive. Kaplan-Meier survival analysis of recurrence-free survival (RFS) in elafin-positive (elafin score > 0) and negative (elafin score = 0) breast cancer cases. Significance calculated by rank-sum test.

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