Figure 3From: Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrenceElafin-positive tumor cells are prognostic of poor RFS in breast cancer. (A) Representative photomicrographs of elafin immunohistochemical (IHC) staining in invasive breast carcinoma demonstrating i and ii: negative (elafin score = 0) and iii to vi: positive (elafin score >0) staining. (B) Frequency of elafin-positive cells in breast tumors by subtype split into the categories 0%, 1 to 10%, 10 to 33%, and greater than 33%. (C, D) Kaplan-Meier survival analysis of elafin-positive and -negative breast cancer cases, significance calculated by rank-sum test. (C) Recurrence-free survival (RFS) and (D) overall survival (OS).Back to article page