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Figure 1 | Breast Cancer Research

Figure 1

From: The Triple-Negative Breast Cancer Database: an omics platform for reference, integration and analysis of triple-negative breast cancer data

Figure 1

Navigation through the Triple-Negative Breast Cancer Database. The Triple Negative Breast Cancer Database (TNBCDb) has features enabled to search molecule types by molecule gene symbol and different accession numbers (Entrez Gene, OMIM, SwissProt and MiRbase IDs). To help researchers search genes by gene symbol, a ‘find your gene’ feature has been incorporated that allows selection of molecules from the browse page or helps find the corresponding gene symbols for your molecule. For each of the microRNAs, mRNAs, proteins or phosphoproteins, their differential regulation in tissues as well as the cell lines is provided as available. The TNBCDb viewer has been enabled to facilitate visualization of the regulation of molecules in triple-negative breast cancer (TNBC) tissue(s) versus different types of non-TNBC tissues and for molecules in one TNBC cell line with another TNBC cell line and with different non-TNBC cell lines highlighting their fold-change values. The network viewer enables the integrated view of the interactions, co-expressions, biological processes, molecular function, cellular compartments and the biological pathways that are reported to be associated with each of the molecules in TNBCDb. Further, researchers can also search by tissue type, cell line name, experiment method and PubMed IDs as individual or multiple queries. The TNBCDb data in the complete form are available for free download [8]. ER, estrogen receptor; Her2, human epidermal growth factor receptor 2; LN, lymph node; PR, progesterone receptor.

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