Table 2 Cox PH models of E2F4 iRAS hazard ratios (HRs) adjusted for clinicopathological data
From: E2F4 regulatory program predicts patient survival prognosis in breast cancer
A | Â | Â | Â | Â | Â |
|---|---|---|---|---|---|
Variable | Type | Hazard ratio | Std. error | 95% CI | Pvalue |
E2F4 iRAS (high vs. low) | Binary | 2.013 | 0.108 | 1.63 - 2.49 | 8.54E-11 |
Age | Continuous | 1.002 | 0.004 | 0.99 - 1.01 | 0.6890 |
ER status (+ vs. -) | Binary | 1.061 | 0.113 | 0.85 - 1.33 | 0.6029 |
Grade | Ordinal | 1.157 | 0.074 | 1.01 - 1.34 | 0.0475 |
Size | Continuous | 1.013 | 0.004 | 1.01 - 1.02 | 0.0001 |
Lymph node status (+ vs. -) | Binary | 1.407 | 0.149 | 1.05 - 1.88 | 0.0215 |
Pharmacological treatment | Binary | 0.651 | 0.148 | 0.49 - 0.87 | 0.0037 |
B | Â | Â | Â | Â | Â |
Variable | Type | Hazard ratio | Std. error | 95% CI | P value |
E2F4 iRAS (high vs. low) | Binary | 1.9013 | 0.0918 | 1.59 - 2.28 | 2.57E-12 |
Adjuvant! risk score (low vs. high) | Binary | 0.6799 | 0.1001 | 0.56 - 0.83 | 0.0001 |
Pharmacological treatment | Binary | 0.8362 | 0.091 | 0.70 - 0.99 | 0.0493 |
C | Â | Â | Â | Â | Â |
Variable | Type | Hazard ratio | Std. error | 95% CI | P value |
E2F4 iRAS (high vs. low) | Binary | 1.86177 | 0.10 | 1.52 - 2.27 | 1.12E-09 |
NPI score | Continuous | 1.29314 | 0.05844 | 1.15 - 1.45 | 1.09E-05 |
Pharmacological treatment | Binary | 0.76527 | 0.09927 | 0.63 - 0.93 | 0.0070 |