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Table 2 Cox PH models of E2F4 iRAS hazard ratios (HRs) adjusted for clinicopathological data

From: E2F4 regulatory program predicts patient survival prognosis in breast cancer

A      
Variable Type Hazard ratio Std. error 95% CI Pvalue
E2F4 iRAS (high vs. low) Binary 2.013 0.108 1.63 - 2.49 8.54E-11
Age Continuous 1.002 0.004 0.99 - 1.01 0.6890
ER status (+ vs. -) Binary 1.061 0.113 0.85 - 1.33 0.6029
Grade Ordinal 1.157 0.074 1.01 - 1.34 0.0475
Size Continuous 1.013 0.004 1.01 - 1.02 0.0001
Lymph node status (+ vs. -) Binary 1.407 0.149 1.05 - 1.88 0.0215
Pharmacological treatment Binary 0.651 0.148 0.49 - 0.87 0.0037
B      
Variable Type Hazard ratio Std. error 95% CI P value
E2F4 iRAS (high vs. low) Binary 1.9013 0.0918 1.59 - 2.28 2.57E-12
Adjuvant! risk score (low vs. high) Binary 0.6799 0.1001 0.56 - 0.83 0.0001
Pharmacological treatment Binary 0.8362 0.091 0.70 - 0.99 0.0493
C      
Variable Type Hazard ratio Std. error 95% CI P value
E2F4 iRAS (high vs. low) Binary 1.86177 0.10 1.52 - 2.27 1.12E-09
NPI score Continuous 1.29314 0.05844 1.15 - 1.45 1.09E-05
Pharmacological treatment Binary 0.76527 0.09927 0.63 - 0.93 0.0070