Skip to main content

Table 4 Numbers of total, proliferative and apoptotic CTCs in serial samples during the dormancy period for DC with a prolonged disease-free status (n = 8)

From: Evaluation of proliferation and apoptosis markers in circulating tumor cells of women with early breast cancer who are candidates for tumor dormancy

Patient number

Dormancy period (yrs)

Test no/(time since surgery yrs)

Status

Total CTCs

Dormant a/Total

Nondormant d/Total (%)

Proliferative b/Nondormant d(%)

Apoptotic c/Nondormant d(%)

9

8

1 (5)

DF

1

100

0

0

0

2 (5.5)

DF

0

0

0

0

0

3 (6)

DF

1

100

0

0

0

4 (6.5)

DF

0

0

0

0

0

5 (7)

DF

0

0

0

0

0

6 (7.5)

DF

0

0

0

0

0

7 (8)

DF

0

0

0

0

0

10

13

1 (5)

DF

1.5

100

0

0

0

2 (8)

DF

0

0

0

0

0

3 (11)

DF

5

60

40

100

0

4 (12)

DF

0.5

100

0

0

0

5 (13)

DF

0.5

0

100

100

0

11

10

1 (7)

DF

1

0

100

0

100

2 (8)

DF

1

0

100

0

100

3 (9)

DF

2

50

50

100

0

4 (10)

DF

2

100

0

0

0

12

13

1 (5)

DF

2

75

25

100

0

2 (5.5)

DF

3.5

100

0

0

0

3 (9.5)

DF

22

75

25

25

75

4 (10.5)

DF

1

0

100

0

100

5 (11.5)

DF

0

0

0

0

0

6 (12)

DF

0

0

0

0

0

7 (13)

DF

0

0

0

0

0

13

10.5

1 (5)

DF

0.5

100

0

0

0

2 (9)

DF

1

100

0

0

0

3 (10.5)

DF

0

0

0

0

0

14

10.5

1 (5)

DF

0

0

0

0

0

2 (6)

DF

0.5

100

0

0

0

3 (10)

DF

0

0

0

0

0

15

8

1 (5)

DF

0.5

100

0

0

0

2 (5.5)

DF

0

0

0

0

0

3 (6)

DF

0.5

100

0

0

0

4 (8)

DF

0

0

0

0

0

16

12

1 (10)

DF

0

0

0

0

0

2 (11)

DF

1

100

0

0

0

3 (12)

DF

31

82

18

0

100

  1. aKi67(-)/M30(-) CTCs, bKi67(+)/M30(-) CTCs, cKi67(-)/M30(+), dKi67(+)/M30(-) or Ki67(-)/M30(+) CTCs. CTCs, circulating tumor cells; DC, dormancy candidates; DF, disease-free.