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Table 1 Characteristics of dormancy candidates

From: Evaluation of proliferation and apoptosis markers in circulating tumor cells of women with early breast cancer who are candidates for tumor dormancy

  CTC-positive CTC-negative  
(n = 40) (n = 82) P
Age, years    
Median (range) 52 (27-75) 57 (31-71) 0.133
  N (%)  
Menopausal status
Premenopausal  21 (52.5) 28 (34.1) 0.152
Postmenopausal 18 (45) 51 (62.2)
UN 1 (2.5) 3 (3.6)
HR status
ER(+) and/or PR(+) 26 (65) 48 (58.5) 0.212
ER(-)/PR(-) 12 (30) 24 (29.3)
UN 2 (5) 10 (12.2)
HER2 status
HER2(+) 9 (22.5) 12 (14.6) 0.252
HER2(-) 29 (72.5) 59 (72)
UN 2 (5) 11 (13.4)
Tumor size
T1 10 (25) 25 (30.5) 0.418
T2 21 (52.5) 45 (54.9)
T3 8 (20) 8 (9.7)
UN 1 (2.5) 4 (4.8)
Grade
I 0 (0) 1 (1.2) 0.938
II 18 (45) 40 (48.8)
III 17 (42.5) 33 (40.2)
Lobular 3 (7.5) 5 (6)
UN 2 (5) 3 (3.6)
Number of positive nodes
0 15 (37.5) 33 (40.2) 0.220
1-3 12 (30) 33 (40.2)
≥4 12 (30) 12 (14.6)
UN 1 (2.5) 4 (4.8)
  1. CTCs, circulating tumor cells; ER, estrogen receptor; HER2, human epidermal growth factor 2; HR, hormone receptor; PR, progesterone receptor; UN, unknown.