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Table 1 Characteristics of dormancy candidates

From: Evaluation of proliferation and apoptosis markers in circulating tumor cells of women with early breast cancer who are candidates for tumor dormancy

 

CTC-positive

CTC-negative

 

(n = 40)

(n = 82)

P

Age, years

   

Median (range)

52 (27-75)

57 (31-71)

0.133

 

N (%)

 

Menopausal status

Premenopausal 

21 (52.5)

28 (34.1)

0.152

Postmenopausal

18 (45)

51 (62.2)

UN

1 (2.5)

3 (3.6)

HR status

ER(+) and/or PR(+)

26 (65)

48 (58.5)

0.212

ER(-)/PR(-)

12 (30)

24 (29.3)

UN

2 (5)

10 (12.2)

HER2 status

HER2(+)

9 (22.5)

12 (14.6)

0.252

HER2(-)

29 (72.5)

59 (72)

UN

2 (5)

11 (13.4)

Tumor size

T1

10 (25)

25 (30.5)

0.418

T2

21 (52.5)

45 (54.9)

T3

8 (20)

8 (9.7)

UN

1 (2.5)

4 (4.8)

Grade

I

0 (0)

1 (1.2)

0.938

II

18 (45)

40 (48.8)

III

17 (42.5)

33 (40.2)

Lobular

3 (7.5)

5 (6)

UN

2 (5)

3 (3.6)

Number of positive nodes

0

15 (37.5)

33 (40.2)

0.220

1-3

12 (30)

33 (40.2)

≥4

12 (30)

12 (14.6)

UN

1 (2.5)

4 (4.8)

  1. CTCs, circulating tumor cells; ER, estrogen receptor; HER2, human epidermal growth factor 2; HR, hormone receptor; PR, progesterone receptor; UN, unknown.