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Table 3 Neonatal androgen effects on tumor incidence (induced by chemical carcinogens)

From: The role of androgens in experimental rodent mammary carcinogenesis

Reference

Animal model

Type of androgen

Dose (mg)

Duration

Incidence

7,12-Dimethylbenz(a)anthracene

    

Kov?cs [52]

Wistar ratsa

TP

2.5

Single injection

?

Shellabarger and Soo [53]

SD rats

TP

1.25

Single injection

?

Christakos and colleagues [54]

SD rats

TP

1.25

Single injection

?

Yoshida and colleagues [55]

SD rats

TP

1.25

Daily until the end of the experiment

?

Purnell [56]

LEW/Mai rats

TP

1.25

Single injection

No effect

Verhoeven and colleagues [57]

Female and male SD rats

TP

0.5

Single injection

No effect

  1. SD, Sprague?Dawley; TP, testosterone propionate. aFemale rats unless otherwise specified.