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Table 1 Liquid chromatography-tandem mass spectrometry identification of proteins differentially secreted by BT-474 wild-type and trastuzumab-resistant BT-474 cells a

From: Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

UniProt accession number

Protein name

Gene name

SI WT

SI TR

Log 2(SI TR/SI WT)

Q16610

Extracellular matrix protein 1

ECM1

0.0762

153.8420

8.94

P27797

Calreticulin

CALR

8.5510

32.8933

1.3853

P07339

Cathepsin D

CTSD

27.7801

168.2733

2.0520

P00338

l-lactate dehydrogenase A chain

LDHA

55.1457

171.2111

1.0651

P04626

Receptor tyrosine protein kinase erbB-2

ERBB2

12.7955

33.2680

0.7694

P17931

Galectin-3

LGALS3

0.4470

9.4270

3.7263

  1. aSI, Spectral index; TR, Trastuzumab-resistant; WT, Wild type.