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Table 1 Liquid chromatography-tandem mass spectrometry identification of proteins differentially secreted by BT-474 wild-type and trastuzumab-resistant BT-474 cells a

From: Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

UniProt accession number Protein name Gene name SI WT SI TR Log 2(SI TR/SI WT)
Q16610 Extracellular matrix protein 1 ECM1 0.0762 153.8420 8.94
P27797 Calreticulin CALR 8.5510 32.8933 1.3853
P07339 Cathepsin D CTSD 27.7801 168.2733 2.0520
P00338 l-lactate dehydrogenase A chain LDHA 55.1457 171.2111 1.0651
P04626 Receptor tyrosine protein kinase erbB-2 ERBB2 12.7955 33.2680 0.7694
P17931 Galectin-3 LGALS3 0.4470 9.4270 3.7263
  1. aSI, Spectral index; TR, Trastuzumab-resistant; WT, Wild type.