Table 1 Properties of breast cancer cell lines used in this study a
Cell lines | Subtype | ER | PR | Her2 | p53 | TGFβ effects | Other properties |
|---|---|---|---|---|---|---|---|
MCF-7 | Luminal | + | + | +/− Wild type | Growth inhibition | ||
MDA-MB-231 | Basal B | − | − | +/+ Mutated | Migration, invasion | ||
SCP2 | Basal B | − | − | Not tested | Migration, invasion | Metastasize to bone | |
BT-549 | Basal B | − | − | +/+ Mutated | Migration, invasion | ||
SUM-149PT | Basal B | − | − | + As per mRNA | Growth inhibition | ||
SUM-159PT | Basal B | − | − | + As per mRNA | Invasion | ||
SK-BR-3 | Luminal | − | − | Overexpress | Mutated | ||
MCF-7 | Luminal | + | + | +/− Wild type | Growth inhibition | ||
MDA-MB-231 | Basal B | − | − | +/+ Mutated | Migration, invasion | ||
SCP2 | Basal B | − | − | Not tested | Migration, invasion | Metastasize to bone | |
BT-549 | Basal B | − | − | +/+ Mutated | Migration, invasion | ||
SUM-149PT | Basal B | − | − | + As per mRNA | Growth inhibition | ||
SUM-159PT | Basal B | − | − | + As per mRNA | Invasion | ||
SK-BR-3 | Luminal | − | − | Overexpress | Mutated |