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Table 1 Subjects in CIMBA and BCAC datasets with breast tumor ER or grade status, by country

From: Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

Country CIMBA BCAC
  Number BRCA1 Number BRCA2 Number BCAC noncarriers
Australia 363 293 2,014
Canada 97 57 927
Denmark 201 151 2,318
Finland 55 64 2,607
Germany 982 493 9,503
Italy 547 362 270
Netherlands 113 32 4,181
Poland 247 0 2,527
Spain 91 102 358
Sweden 158 34 5,266
United Kingdom 642 388 12,989
USA 981 589 4,605
Total 4,477 2,565 47,565
  1. Data for primary breast tumor. ER, breast tumor estrogen receptor status; BCAC, Breast Cancer Association Consortium; CIMBA, Consortium for Investigator of Modifiers of BRCA1 and BRCA2.
  2. ER status was missing for 548 (12.2%) BRCA1 carriers, 292 (11.4%) BRCA2 carriers and 4,942 (10.4%) presumed noncarriers. Histological grade was missing for 890 (19.9%) BRCA1 carriers, 555 (21.6%) BRCA2 carriers, and 6,020 (12.7%) presumed noncarriers.