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Table 1 Subjects in CIMBA and BCAC datasets with breast tumor ER or grade status, by country

From: Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

Country

CIMBA

BCAC

 

Number BRCA1

Number BRCA2

Number BCAC noncarriers

Australia

363

293

2,014

Canada

97

57

927

Denmark

201

151

2,318

Finland

55

64

2,607

Germany

982

493

9,503

Italy

547

362

270

Netherlands

113

32

4,181

Poland

247

0

2,527

Spain

91

102

358

Sweden

158

34

5,266

United Kingdom

642

388

12,989

USA

981

589

4,605

Total

4,477

2,565

47,565

  1. Data for primary breast tumor. ER, breast tumor estrogen receptor status; BCAC, Breast Cancer Association Consortium; CIMBA, Consortium for Investigator of Modifiers of BRCA1 and BRCA2.
  2. ER status was missing for 548 (12.2%) BRCA1 carriers, 292 (11.4%) BRCA2 carriers and 4,942 (10.4%) presumed noncarriers. Histological grade was missing for 890 (19.9%) BRCA1 carriers, 555 (21.6%) BRCA2 carriers, and 6,020 (12.7%) presumed noncarriers.