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Figure 6 | Breast Cancer Research

Figure 6

From: Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: a phase 1 proof of principle trial

Figure 6

Effect of treatment with pasireotide on phospho AKT and ERK1/2. (A) The mean intensity index was decreased by pasireotide from 42.5 ± 14 to 9.37 ± 3 after treatment as measured in eight patients. (B) Similar effects were observed with phospho ERK1/2 with a mean intensity index of 218 ± 29 before to 100 ± 18 after treatment, measured in six patients. Control tissues were not affected for p-AKT (C) or p-ERK 1/2 (D).

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