Table 3 Standardized incidence ratios of metachronous contralateral breast cancer stratified by hormone receptor (HR)-status and age in Brandenburg, Munich and Saarland overall, 1998 to 2007
From: Risk of contralateral second primary breast cancer according to hormone receptor status in Germany
Women with first primary age <50 | Women with first primary age ≥50 | |||||
|---|---|---|---|---|---|---|
O | SIR | 95%CI | O | SIR | 95%CI | |
Any first primary | 9,684 | 40,120 | ||||
Any second primary | 144 | 4.0 | 3.4-4.7 | 450 | 1.0 | 0.9-1.1 |
First primary HR-positive | 6,129 | 25,735 | ||||
Any second primary | 51 | 2.2 | 1.7-2.9 | 248 | 0.8 | 0.7-0.9 |
Second primary HR-positive | 25 | 1.7 | 1.2-2.5 | 139 | 0.6 | 0.5-0.7 |
Second primary HR-negative | 7 | 1.8 | 0.8-3.5 | 43 | 1.0 | 0.8-1.4 |
Second primary HR-mixed | 11 | 4.8 | 2.5-8.4 | 38 | 1.0 | 0.7-1.4 |
First primary HR-negative | 1,895 | 4,758 | ||||
Any second primary | 60 | 9.2 | 7.1-11.9 | 104 | 2.0 | 1.7-2.5 |
Second primary HR-positive | 8 | 2.6 | 1.4-4.5 | 31 | 0.9 | 0.7-1.3 |
Second primary HR-negative | 33 | 25.4 | 17.6-35.4 | 46 | 6.1 | 4.5-8.1 |
Second primary HR-mixed | 12 | 18.1 | 9.6-31.1 | 12 | 2.3 | 1.3-3.7 |