Table 2 Standardized incidence ratios of metachronous contralateral breast cancer stratified by hormone receptor (HR)-status in Brandenburg, Munich and Saarland, 1998 to 2007

Any first primary

15,226

26,315

8,263

49,804

  Any second primary

185

1.5

1.3-1.7

287

1.0

0.9-1.1

122

1.4

1.2-1.7

594

1.2

1.1-1.3

  Second primary HR-positive

71

0.9

0.7-1.2

137

0.8

0.6-0.9

33

1.1

0.9-1.4

241

0.9

0.8-1.0

  Second primary HR-negative

68

3.3

2.6-4.2

62

2.1

1.6-2.7

23

2.3

1.5-3.2

153

2.5

2.1-2.9

  Second primary HR-mixed

38

1.9

1.4-2.6

54

1.8

1.3-2.3

14

2.0

1.2-2.9

106

2.0

1.7-2.4

First primary HR-positive

9,698

17,286

4,880

31,864

  Any second primary

97

1.1

0.9-1.4

149

0.8

0.6-0.9

53

1.0

0.8-1.4

299

0.9

0.8-1.0

  Second primary HR-positive

44

0.8

0.6-1.0

94

0.6

0.5-0.7

26

0.9

0.6-1.2

164

0.7

0.6-0.8

  Second primary HR-negative

31

2.1

1.4-3.0

17

0.8

0.5-1.2

2

50

1.1

0.8-1.4

  Second primary HR-mixed

19

1.3

0.8-2.0

24

1.0

0.6-1.5

6

1.1

0.5-2.1

49

1.2

0.9-1.6

First primary HR-negative

2,731

2,758

1,164

6,653

  Any second primary

61

3.0

2.3-3.9

69

2.7

2.1-3.4

34

3.2

2.2-4.5

164

2.8

2.4-3.3

  Second primary HR-positive

20

1.6

1.0-2.4

17

1.0

0.6-1.5

2

39

1.1

0.8-1.5

  Second primary HR-negative

31

8.5

5.8-12.0

30

8.9

6.1-12.7

18

9.6

5.8-14.9

79

8.9

7.1-11.1

  Second primary HR-mixed

7

2.4

1.0-4.8

14

4.3

2.4-7.1

3

24

3.7

2.5-5.2

First primary HR- mixed

1,682

2,524

969

5,175

  Any second primary

26

1.8

1.2-2.7

33

1.2

0.8-1.7

17

1.4

0.8-2.3

76

1.4

1.1-1.8

  Second primary HR-positive

7

0.8

0.3-1.6

9

0.5

0.3-0.9

1

17

0.6

0.4-0.9

  Second primary HR-negative

6

2.5

0.9-5.4

8

2.5

1.1-4.8

2

16

2.2

1.3-3.5

  Second primary HR-mixed

12

5.0

2.6-8.7

11

3.2

1.7-5.7

4

27

4.2

2.8-5.9