From: Risk of contralateral second primary breast cancer according to hormone receptor status in Germany
Brandenburg | Munich | Saarland | Pooled | |
---|---|---|---|---|
Registered cases of invasive first primary breast cancer (n) | 15,226 | 26,315 | 8,263 | 49,804 |
Histological verification (%) | 94.6 | 92.5 | 96.8 | 93.8 |
Receptor status information (%) | ||||
Estrogen positive | 72.1 | 72.6 | 69.0 | 71.9 |
negative | 20.9 | 13.5 | 16.0 | 16.2 |
missing | 7.0 | 13.9 | 15.0 | 11.9 |
Progesterone positive | 66.6 | 68.8 | 61.0 | 66.9 |
negative | 26.1 | 17.0 | 23.9 | 20.9 |
missing | 7.3 | 14.2 | 15.1 | 12.2 |
Median (IQR) age at diagnosis of first primary breast cancer | 63 (52-72) | 63 (53-73) | 64 (54-74) | 63 (53-73) |
Person-years of observation | 57,108 | 92,247 | 31,413 | 180,768 |
Median (IQR) years of follow-up | 3.3 (1.3-5.9) | 3.0 (1.1-5.4) | 3.4 (1.3-6.0) | 3.1 (1.2-5.7) |
Registered cases of metachronous contralateral breast cancer (n) | 185 | 287 | 122 | 594 |
Histological verification (%) | 98.4 | 100.0 | 99.2 | 99.3 |
Receptor status information (%) | ||||
Estrogen positive | 53.0 | 61.0 | 37.7 | 53.7 |
negative | 42.7 | 27.2 | 19.7 | 30.5 |
missing | 4.3 | 11.8 | 42.6 | 15.8 |
Progesterone positive | 44.3 | 53.3 | 27.9 | 45.3 |
negative | 51.4 | 34.8 | 29.5 | 38.9 |
missing | 4.3 | 11.8 | 42.6 | 15.8 |