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Table 4 Numbers reclassified (absolute risk of developing breast cancer within the next 10 years 3%, 3 to 5%, 5 to 8%, 8 +%) for the Tyrer-Cuzick (TC) risk score modified using percent dense area compared to the Tyrer-Cuzick risk score modified using the density residual

From: Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I

TC + unadjusted density/TC + density residual <3% 3-5% 5-8% 8%+ Total
Control      
<3% 4 (100%) 0 (0%) 0 (0%) 0 (0%) 4 (1%)
3-5% 47 (89%) 6 (11%) 0 (0%) 0 (0%) 53 (11%)
5-8% 19 (13%) 105 (70%) 25 (17%) 0 (0%) 149 (31%)
8 +% 0 (0%) 29 (10%) 128 (47%) 117 (43%) 274 (57%)
Total 70 (15%) 140 (29%) 153 (32%) 117 (24%) 480 (100%)
Case      
<3% 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
3-5% 6 (55%) 5 (45%) 0 (0%) 0 (0%) 11 (15%)
5-8% 1 (6%) 15 (83%) 2 (11%) 0 (0%) 18 (25%)
8 +% 0 (0%) 4 (9%) 11 (26%) 28 (65%) 43 (60%)
Total 7 (10%) 24 (33%) 13 (18%) 28 (39%) 72 (100%)