Skip to main content

Table 3 Numbers reclassified (absolute risk of developing breast cancer within the next 10 years 3%, 3 to 5%, 5 to 8%, 8 +%) for the Tyrer-Cuzick (TC) risk score compared to Tyrer-Cuzick risk score modified using the density residual

From: Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I

TC/TC + density residual

<3%

3-5%

5-8%

8%+

Total

Control

     

<3%

10 (67%)

4 (27%)

1 (7%)

0 (0%)

15 (3%)

3-5%

52 (30%)

65 (38%)

44 (26%)

10 (6%)

171 (36%)

5-8%

8 (3%)

68(29%)

92 (39%)

66 (28%)

234 (49%)

8 +%

0 (0%)

3 (5%)

16 (27%)

41 (68%)

60 (12%)

Total

70 (15%)

140 (29%)

153 (32%)

117 (24%)

480 (100%)

Case

     

<3%

2 (50%)

2 (50%)

0 (0%)

0 (0%)

4 (6%)

3-5%

5 (17%)

13 (43%)

7 (23%)

5 (17%)

30 (42%)

5-8%

0 (0%)

9 (39%)

5 (22%)

9 (39%)

23 (32%)

8 +%

0 (0%)

0 (0%)

1 (7%)

14 (93%)

15 (21%)

Total

7 (10%)

24 (33%)

13 (18%)

28 (39%)

72 (100%)