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Figure 7 | Breast Cancer Research

Figure 7

From: Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers

Figure 7

Nucleolar DDX21 promotes rRNA processing in breast cancer cells. (A) HCC1806 cells were infected with shSCR or shRNA-DDX21, two days postinfection, cells were pulsed with [3H-methyl] methionine and chased for 1 hour. Total RNA was extracted and analyzed for 47S, 32S, 28S and 18S rRNA levels. Methylene blue-stained membrane is also shown at the bottom. (B) HCC1806 cells were infected with shSCR or shRNA-DDX21, two days postinfection, cells were pulsed with [3H-methyl] methionine and chased for 0, 25 and 50 min. Total RNA was extracted and analyzed for 47S, 32S, 28S and 18S rRNA levels. Methylene blue-stained membrane is also shown at the bottom.

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