Figure 3

Association of baseline circulating tumor cell counts with metastatic spread in patients with single-site disease. (A) Type of the first progression of disease (PD) occurring after baseline in 112 patients with single metastatic site disease, stratified by circulating tumor cell (CTC) count. Thirty-four (23.3%) of the total one hundred forty-six patients with single-site disease had not developed PD before the last follow-up visit. (B), (C) and (D) Time to new metastatic sites (B), time to new metastatic lesions (C) and overall survival (D) in the 146 patients with single metastatic site disease, stratified by CTC count.