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Figure 1 | Breast Cancer Research

Figure 1

From: Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways

Figure 1

An overview of the workflow and mass spectrometric phosphotyrosine profiling of mouse tumours. (A) Schematic of the workflow in this study. Ab, Antibody; IP, Immunoprecipitation; nanoLC-MS/MS, Nano-liquid chromatography tandem mass spectrometry; PyMT, Polyoma virus middle T antigen. (B) Distribution and overlap of the 763 phosphotyrosine (pY) sites identified in the three mouse tumour models. (C) Distribution and overlap of the 381 highly reproducible pY sites identified in the three mouse tumour models.

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Breast Cancer Research

ISSN: 1465-542X

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