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Table 1 A representative list of target genes for miR-638

From: miR-638 mediated regulation of BRCA1affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer

Target gene

Representative transcript

Gene name

Conserved sites

   

Total context + score

   

Total

8-mer

7mer-m8

7mer-1A

 

STARD10

NM_006645

StAR-related lipid transfer (START) domain containing 10

1

1

0

0

−0.53

NPAS4

NM_178864

neuronal PAS domain protein 4

1

1

0

0

−0.44

MKLN1

NM_001145354

muskelin 1, intracellular mediator containing kelch motifs

1

0

0

1

−0.27

CCDC92

NM_025140

coiled-coil domain containing 92

1

0

0

1

−0.26

SHPK

NM_013276

sedoheptulokinase

1

0

0

1

−0.26

RIMKLB

NM_020734

ribosomal modification protein rimK-like family member B

1

0

1

0

−0.24

PGK1

NM_000291

phosphoglycerate kinase 1

1

0

0

1

−0.22

HP1BP3

NM_016287

heterochromatin protein 1, binding protein 3

1

0

0

1

−0.21

LMO4

NM_006769

LIM domain only 4

1

0

0

1

−0.21

PAK2

NM_002577

p21 protein (Cdc42/Rac)-activated kinase 2

1

0

0

1

−0.2

MARCKS

NM_002356

myristoylated alanine-rich protein kinase C substrate

1

0

0

1

−0.19

FRMPD4

NM_014728

FERM and PDZ domain containing 4

1

0

0

1

−0.18

EMILIN3

NM_052846

elastin microfibril interfacer 3

1

0

0

1

−0.18

MYCL1

NM_001033081

v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)

1

0

0

1

−s0.18

LOC100507050

NM_001195528

hypothetical LOC100507050

1

0

0

1

−0.18

ISOC2

NM_001136201

isochorismatase domain containing 2

1

0

0

1

−0.18

EDN3

NM_207032

endothelin 3

1

0

0

1

−0.18

BRCA1

NM_007294

breast cancer 1, early onset

1

0

0

1

−0.16

TSPAN1

NM_005727

tetraspanin 1

1

0

0

1

−0.16

BUB3

NM_004725

budding uninhibited by benzimidazoles 3 homolog (yeast)

1

0

0

1

−0.15

SP8

NM_182700

Sp8 transcription factor

1

0

0

1

−0.15

ZNF24

NM_006965

zinc finger protein 24

1

0

0

1

−0.14

KDSR

NM_002035

3-ketodihydrosphingosine reductase

1

0

0

1

−0.14

KPNA6

NM_012316

karyopherin alpha 6 (importin alpha 7)

1

0

0

1

−0.13

SP7

NM_001173467

Sp7 transcription factor

1

0

0

1

−0.12

NOVA1

NM_002515

neuro-oncological ventral antigen 1

1

0

0

1

−0.11

SENP1

NM_014554

SUMO1/sentrin specific peptidase 1

1

0

0

1

−0.06

SRSF1

NM_001078166

serine/arginine-rich splicing factor 1

1

0

0

1

−0.05

EPHA7

NM_004440

EPH receptor A7

1

0

0

1

−0.04

TTC28

NM_001145418

tetratricopeptide repeat domain 28

1

0

0

1

−0.04