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Table 1 General characteristics of primary tumor samples from 123 patients with hormone receptor–negative breast cancers a

From: Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A–dependent phospho-Akt inactivation in estrogen receptor–negative human breast cancer cells

Characteristic N = 123 %
Median age, yr (IQR) 54 (48 to 66)
Tumor stage 32 26.0
T1 79 64.2
T2 7 5.7
T3 4 3.3
T4 1 0.8
Node-positive disease 57 47.3
Metastatic disease 6 4.9
TNM stage   
I 19 15.4
II 70 56.9
III 28 22.8
IV 6 4.9
HER2-positiveb 53 43.1
CIP2A expression   
Negative 4 3.3
Low 44 35.8
Moderate 55 44.7
High 20 16.3
Positive p-Akt expression 120 97.6
  1. aCIP2A, Cancerous inhibitor of protein phosphatase 2A HER2, Human epidermal growth factor receptor 2. bHER2-positive was defined as an immunohistochemical staining score of 3+ or 2+ with gene amplification shown by fluorescence in situ hybridization.