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Table 1 General characteristics of primary tumor samples from 123 patients with hormone receptor–negative breast cancers a

From: Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A–dependent phospho-Akt inactivation in estrogen receptor–negative human breast cancer cells

Characteristic

N = 123

%

Median age, yr (IQR)

54 (48 to 66)

Tumor stage

32

26.0

T1

79

64.2

T2

7

5.7

T3

4

3.3

T4

1

0.8

Node-positive disease

57

47.3

Metastatic disease

6

4.9

TNM stage

  

I

19

15.4

II

70

56.9

III

28

22.8

IV

6

4.9

HER2-positiveb

53

43.1

CIP2A expression

  

Negative

4

3.3

Low

44

35.8

Moderate

55

44.7

High

20

16.3

Positive p-Akt expression

120

97.6

  1. aCIP2A, Cancerous inhibitor of protein phosphatase 2A HER2, Human epidermal growth factor receptor 2. bHER2-positive was defined as an immunohistochemical staining score of 3+ or 2+ with gene amplification shown by fluorescence in situ hybridization.
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Breast Cancer Research

ISSN: 1465-542X

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