TY - JOUR AU - Heidary, Maryam AU - Auer, Martina AU - Ulz, Peter AU - Heitzer, Ellen AU - Petru, Edgar AU - Gasch, Christin AU - Riethdorf, Sabine AU - Mauermann, Oliver AU - Lafer, Ingrid AU - Pristauz, Gunda AU - Lax, Sigurd AU - Pantel, Klaus AU - Geigl, Jochen B. AU - Speicher, Michael R. PY - 2014 DA - 2014/08/09 TI - The dynamic range of circulating tumor DNA in metastatic breast cancer JO - Breast Cancer Research SP - 421 VL - 16 IS - 4 AB - The management of metastatic breast cancer needs improvement. As clinical evaluation is not very accurate in determining the progression of disease, the analysis of circulating tumor DNA (ctDNA) has evolved to a promising noninvasive marker of disease evolution. Indeed, ctDNA was reported to represent a highly sensitive biomarker of metastatic cancer disease directly reflecting tumor burden and dynamics. However, at present little is known about the dynamic range of ctDNA in patients with metastatic breast cancer. SN - 1465-542X UR - https://doi.org/10.1186/s13058-014-0421-y DO - 10.1186/s13058-014-0421-y ID - Heidary2014 ER -