Figure 5
From: A joint analysis of metabolomics and genetics of breast cancer
Correlation between selected metabolite levels and BRCA1 mRNA expression. Three representative metabolites (coenzyme A (CoA), reduced glutathione (GSH) and oleoyl-carnitine) that are positively and three (N-acetylneuraminate, arachidonate and palmitate) that are inversely correlated with BRCA1 mRNA levels from The Cancer Genome Atlas (TCGA) RNAseq data on 23 cancers are shown. The full list of metabolites correlated with BRCA1 is provided in Table S6 in Additional file 7 showing listing both normalized metabolite levels and metabolite levels with an additional log2 transformation to reduce the impact of outliers.