Table 2 Linear regression of factors associated with telomere length
From: Physical activity and telomere length in early stage breast cancer survivors
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Coefficient (95% CI) | P | Adjusted coefficient (95% CI) | P | |
| Physical activity | ||||
| Moderate to vigorous (reference) | 1 | 1 | ||
| None | −0.27 (−0.08, −0.46) | 0.006 | −0.22 (−0.41, −0.03) | 0.03 |
| Age, years | ||||
| <55 (reference) | 1 | 1 | ||
| 55 to 65 | −0.12 (−0.30, 0.07) | 0.22 | −0.09 (−0.28, 0.10) | 0.33 |
| >65 | −0.33 (−0.52, −0.13) | 0.001 | −0.26 (−0.47, 0.04) | 0.02 |
| Body mass index | ||||
| <25 | a1 | |||
| 25 to 30 | −0.01 (−0.19, 0.16) | 0.88 | ||
| >30 | −0.13 (−0.031, 0.05) | 0.16 | ||
| Smoking status | ||||
| Never (reference) | 1 | |||
| Current | −0.11 (−0.52, 0.30) | 0.60 | ||
| Previous | −0.09 (−0.24, 0.06) | 0.22 | ||
| Race/ethnicity | ||||
| White | a1 | |||
| Non-white* | −0.03 (−0.22, 0.16) | 0.74 | ||
| Educational level | ||||
| High school or less | a1 | |||
| College | 0.07 (−0.12, 0.26) | 0.48 | ||
| Graduate or higher | 0.16 (−0.04, 0.36) | 0.11 | ||
| Marital status | ||||
| Married/partnered | a1 | |||
| Single | −0.02 (−0.18, 0.13) | 0.76 | ||
| Stage | ||||
| 0 and I (reference) | 1 | |||
| II | 0.04 (−0.11, 0.20) | 0.58 | ||
| III | 0.06 (−0.18, 0.31) | 0.60 | ||
| Previous chemotherapy | ||||
| No chemotherapy (reference) | 1 | 1 | ||
| Chemotherapy | 0.19 (0.04, 0.34) | 0.01 | 0.07 (−0.09, 0.24) | 0.38 |
| Current aromatase inhibitor | ||||
| None (reference) | ||||
| Letrozole | 0.09 (−0.19, 0.38) | 0.53 | ||
| Anastrozole | −0.01 (−0.26, 0.23) | 0.93 | ||
| Exemestane | 0.03 (−0.28, 0.34) | 0.84 | ||
| Cormorbid conditions | ||||
| None (reference) | 1 | |||
| One | −0.02 (−0.25, 0.21) | 0.86 | ||
| Two or more | −0.11 (−0.32, 0.10) | 0.29 | ||
| Anxiety | ||||
| Normal (reference) | 1 | |||
| Symptomatic | −0.01 (−0.18, 0.16) | 0.93 | ||
| Depression | ||||
| Normal (reference) | 1 | |||
| Symptomatic | 0.05 (−0.21, 0.31) | 0.70 | ||
