From: Physical activity and telomere length in early stage breast cancer survivors
 | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Coefficient (95% CI) | P | Adjusted coefficient (95% CI) | P | |
Physical activity | Â | Â | Â | Â |
  Moderate to vigorous (reference) | 1 |  | 1 |  |
  None | −0.27 (−0.08, −0.46) | 0.006 | −0.22 (−0.41, −0.03) | 0.03 |
Age, years | Â | Â | Â | Â |
  <55 (reference) | 1 |  | 1 |  |
  55 to 65 | −0.12 (−0.30, 0.07) | 0.22 | −0.09 (−0.28, 0.10) | 0.33 |
  >65 | −0.33 (−0.52, −0.13) | 0.001 | −0.26 (−0.47, 0.04) | 0.02 |
Body mass index | Â | Â | Â | Â |
  <25 | a1 |  |  |  |
  25 to 30 | −0.01 (−0.19, 0.16) | 0.88 |  |  |
  >30 | −0.13 (−0.031, 0.05) | 0.16 |  |  |
Smoking status | Â | Â | Â | Â |
  Never (reference) | 1 |  |  |  |
  Current | −0.11 (−0.52, 0.30) | 0.60 |  |  |
  Previous | −0.09 (−0.24, 0.06) | 0.22 |  |  |
Race/ethnicity | Â | Â | Â | Â |
  White | a1 |  |  |  |
  Non-white* | −0.03 (−0.22, 0.16) | 0.74 |  |  |
Educational level | Â | Â | Â | Â |
  High school or less | a1 |  |  |  |
  College | 0.07 (−0.12, 0.26) | 0.48 |  |  |
  Graduate or higher | 0.16 (−0.04, 0.36) | 0.11 |  |  |
Marital status | Â | Â | Â | Â |
  Married/partnered | a1 |  |  |  |
  Single | −0.02 (−0.18, 0.13) | 0.76 |  |  |
Stage | Â | Â | Â | Â |
  0 and I (reference) | 1 |  |  |  |
  II | 0.04 (−0.11, 0.20) | 0.58 |  |  |
  III | 0.06 (−0.18, 0.31) | 0.60 |  |  |
Previous chemotherapy | Â | Â | Â | Â |
  No chemotherapy (reference) | 1 |  | 1 |  |
  Chemotherapy | 0.19 (0.04, 0.34) | 0.01 | 0.07 (−0.09, 0.24) | 0.38 |
Current aromatase inhibitor | Â | Â | Â | Â |
  None (reference) |  |  |  |  |
  Letrozole | 0.09 (−0.19, 0.38) | 0.53 |  |  |
  Anastrozole | −0.01 (−0.26, 0.23) | 0.93 |  |  |
  Exemestane | 0.03 (−0.28, 0.34) | 0.84 |  |  |
Cormorbid conditions | Â | Â | Â | Â |
  None (reference) | 1 |  |  |  |
  One | −0.02 (−0.25, 0.21) | 0.86 |  |  |
  Two or more | −0.11 (−0.32, 0.10) | 0.29 |  |  |
Anxiety | Â | Â | Â | Â |
  Normal (reference) | 1 |  |  |  |
  Symptomatic | −0.01 (−0.18, 0.16) | 0.93 |  |  |
Depression | Â | Â | Â | Â |
  Normal (reference) | 1 |  |  |  |
  Symptomatic | 0.05 (−0.21, 0.31) | 0.70 |  |  |