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Table 1 Correlation between Cox-2 and Ido-1 expression and various clinicopathologic factors

From: Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

Parameters Category No. of cases Cox-2 expression (tumor) Pvalue Ido-1 expression (CAF) Pvalue
Low exp. High exp. Low exp. High exp.
Age (years) <60 years 141 73 68 0.444 69 72 0.647
  60 years 61 28 33   32 29  
Primary tumor (T) T1 82 45 37 0.002 44 38 <0.001
  T2 96 52 44   54 42  
  T3-4 24 4 20   3 21  
Nodal status (N) N0 117 77 40 <0.001 76 41 <0.001
  N1-N2 85 24 61   25 60  
Stage I 63 37 26 0.006 37 26 0.002
  II 115 59 56   60 55  
  III 24 5 19   4 20  
Histologic grade Grade I 18 13 5 0.122 15 3 0.003
  Grade II 141 69 72   71 70  
  Grade III 43 19 24   15 28  
CAF Ido-1 expression Low Exp. (<medium) 101 65 35 <0.001    
  High Exp. (medium) 101 35 65     
  1. Bold figures, Statistically significant.