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Table 2 Polysomy 17 according to immunohistochemical scoring and fluorescence in situ hybridization analysis

From: Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and immunohistochemistry

  Polysomy 17 Non-polysomy 17
IHC score FISH normal FISH amplified Polysomy 17 (%) FISH normal FISH amplified
0 0/8 0/0 0 8/8 0/0
1+ 0/20 0/0 0 20/20 0/0
2+ 13/66 0/12 17 53/66 12/12
3+ 1/1 8/68 15 0/1 60/68
Total 14/95 (15%) 8/80 (10%) 13 81/95 (85%) 72/80 (90%)
  1. FISH, fluorescence in situ hybridization; IHC, immunohistochemistry.