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Table 2 Polysomy 17 according to immunohistochemical scoring and fluorescence in situ hybridization analysis

From: Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and immunohistochemistry

 

Polysomy 17

Non-polysomy 17

IHC score

FISH normal

FISH amplified

Polysomy 17 (%)

FISH normal

FISH amplified

0

0/8

0/0

0

8/8

0/0

1+

0/20

0/0

0

20/20

0/0

2+

13/66

0/12

17

53/66

12/12

3+

1/1

8/68

15

0/1

60/68

Total

14/95 (15%)

8/80 (10%)

13

81/95 (85%)

72/80 (90%)

  1. FISH, fluorescence in situ hybridization; IHC, immunohistochemistry.