Table 2 Myofibroblast-related genes that are differentially upregulated in fibroblasts activated by serum compared with serum-starved fibroblasts
Gene symbol | Gene name | Fold increase in signal intensity in serum-activated fibroblasts versus serum depleted fibroblasts (P < 0.001) |
|---|---|---|
LOXL2 | Lysyl oxidase-like 2 | 8.2 |
PLOD2 | Procollagen-lysine, 2 oxoglutarate 5-dioxygenase | 16 |
PLAUR | Plasminogen activator urokinase receptor | 5.3 |
TAGLN | Transgelin | 6.0 |
TPM2 | Tropomysin 2 (beta) | 4.6 |
MYL6 | Myosin, light polypeptide 6, alkaline, smooth muscle | 5.7 |
TFPI2 | Tissue factor pathway inhibitor 2 | 4.8 |
SMAD3 | Mothers against decapentaplegic homolog 3 (Drosophila) | 4.0 |
CXCL12 | Chemokine (C-X-C motif) ligand 12 | 4.5 |
TGFB1 | TGF-β, induced | 26.5 |
LTBP2 | Latent TGF-β binding protein 2 | 30.2 |
COX2 | Cyclo-oxygenase-2 | 16.4 |
CLIC4 | Chloride intracellular channel 4 | 32 |