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Table 2 Myofibroblast-related genes that are differentially upregulated in fibroblasts activated by serum compared with serum-starved fibroblasts

From: Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts

Gene symbol Gene name Fold increase in signal intensity in serum-activated fibroblasts versus serum depleted fibroblasts (P < 0.001)
LOXL2 Lysyl oxidase-like 2 8.2
PLOD2 Procollagen-lysine, 2 oxoglutarate 5-dioxygenase 16
PLAUR Plasminogen activator urokinase receptor 5.3
TAGLN Transgelin 6.0
TPM2 Tropomysin 2 (beta) 4.6
MYL6 Myosin, light polypeptide 6, alkaline, smooth muscle 5.7
TFPI2 Tissue factor pathway inhibitor 2 4.8
SMAD3 Mothers against decapentaplegic homolog 3 (Drosophila) 4.0
CXCL12 Chemokine (C-X-C motif) ligand 12 4.5
TGFB1 TGF-β, induced 26.5
LTBP2 Latent TGF-β binding protein 2 30.2
COX2 Cyclo-oxygenase-2 16.4
CLIC4 Chloride intracellular channel 4 32
  1. TGF, transforming growth factor.