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Table 1 Clinicopathological data and focal adhesion kinase expression in 162 node-negative breast cancers

From: High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome

 

Focal adhesion kinase expression

P value*

 

Negative

Strong

Intermediate

 

Total adenocarcinoma

13 (8%)

30 (18.5%)

119 (73.5%)

 

Tumor type

   

Not significant

   Invasive ductal

5 (4.1%)

27 (22.5%)

88 (72.7%)

 

   Invasive lobular

3 (13%)

2 (8.7%)

18 (78.3%)

 

   Mucinous

5 (62.5%)

/

3 (37.5%)

 

   Tubulo/tubulo-lobular

/

/

5 (100%)

 

   Others

/

1 (16.7%)

5 (88.3%)

 

Histological grade

   

P = 0.038*

   Well differentiated

4 (11.4%)

3 (8.6%)

28 (80%)

 

   Moderately differentiated

6 (7%)

13 (15.1%)

67 (77.9%)

 

   Poorly differentiated

3 (7.3%)

14 (34.1%)

24 (58.5%)

 

Tumor size

   

Not significant

   pT1(a,b,c)

7 (7.2%)

21 (21.6%)

69 (71.1%)

 

   pT2

5 (7.9%)

9 (14.3%)

49 (77.8%)

 

   pT3 and pT4

1 (50%)

 

1 (50%)

 
  1. * P value of chi-squared analysis.