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Table 2 Relation of Q356R and breast cancer risk in the Nurses' Health Study

From: Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer

Genotype

Case (frequency)a

Control (frequency)a

OR (95% CI)

ORb (95% CI)

Q356Q

1065 (86.23)

1413 (87.01)

1.00 (reference)

1.00 (reference)

Q356R

165 (13.36)

206 (12.68)

1.06 (0.85–1.32)

1.05 (0.84–1.32)

R356R

5 (0.4)

5 (0.31)

1.33 (0.38–4.59)

1.67 (0.44–6.35)

  1. CI, confidence interval; OR, odds ratio.
  2. aSamples lacking genotype information were removed from analysis.
  3. bLogistic regression controlling for age, age of menopause, post-menopausal hormone use, age at first birth, parity, family history of breast cancer, and history of benign breast disease.
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Breast Cancer Research

ISSN: 1465-542X

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