Figure 3
From: Letrozole sensitizes breast cancer cells to ionizing radiation
Potentiation of radiation-induced growth inhibition by letrozole measured by clonogenic assay. With radiation alone the MCF-7CA cell survival fraction decreased in a dose-dependent manner, which was significantly potentiated by the addition of 0.7 μM letrozole. For 2 Gy radiation, the surviving fraction was 0.66 with radiation alone and was 0.46 with the addition of letrozole (P = 0.02). For 3 Gy radiation, the corresponding surviving fractions were 0.4 and 0.18, respectively (P = 0.02).