Figure 1
Histopathology of tumours in (BALB/cHeA × MSM/Ms)F1 mice with genotypes p53 +/- Atm +/-, p53 +/- Atm +/+ or p53 +/+ Atm +/-. (a, b) Spontaneously developing mammary adenocarcinoma from p53 +/- Atm +/- mouse. (c, d) Mammary adenocarcinoma from X-irradiated p53 +/- Atm +/- mouse. (e, f) Mammary adenocarcinoma from X-irradiated p53 +/- Atm +/+ mouse. (g) Osteosarcoma observed in nonirradiated p53 +/- Atm +/- mouse. (h) Thymic lymphoma from p53 +/+ Atm +/- mouse exposed to X-rays. Panels a, c and e: 40×. Panels b, d, f, g and h: 100×.