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Table 3 Interferon-γ ELISPOT assay after vaccination with virus-like replicon particles (VRP)-neu or VRP-hemagglutinin (HA)

From: Alphavirus replicon particles containing the gene for HER2/neuinhibit breast cancer growth and tumorigenesis

Effector:stimulator VRP-neu (spots/106 cells) VRP-HA (spots/106 cells)
100:1 99a 11
50:1 126a 17
25:1 129a 25
Effector only 2 5
Concanavalin A 256a,b Not determined
  1. a P = 0.05 by Student's t test.
  2. bSpleen cells stimulated with concanavalin A as a positive control for the assay.