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Table 3 Association between the CYP19 and CYP17 variant alleles and breast cancer

From: Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association study

  

Nonfounder statistic

Founder statistic

Variant allele(s)

Estimated allele frequency (%)

Recessive model

Dominant model

Additive model

Recessive model

Dominant model

Additive model

CYP17

       

   C

42.46

- 1.01

- 1.52

- 1.85

0.40

1.08

1.01

P

 

0.16

0.06

0.03

0.34

0.14

0.16

CYP19

       

   (TTTA)≥10

33.71

- 1.24

1.26

0.32

- 0.32

1.66

1.13

P

 

0.11

0.10

0.38

0.37

0.05

0.13

   (TTTA)11

28.78

- 1.09

1.83

0.97

- 1.50

1.96

0.89

P

 

0.14

0.03

0.17

0.07

0.03

0.19

  1. P values are based on one-tailed test statistics. Values that are statistically significant at one-tailed test are displayed in bold type.
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Breast Cancer Research

ISSN: 1465-542X

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