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Table 2 5-Bromo-2'-deoxyuridine (BrdU) labeling* of MCF10AT cells grown in monoculture and in co-cultures with normal breast-associated fibroblasts (NAF) and carcinoma-associated fibroblasts (CAF)

From: Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture

Culture

BrdU-labeling indices of MCF10AT cells (mean ± standard error of the mean)

BrdU-labeling indices of MCF10AT cells (group mean ± standard error of the mean)

Comparison of BrdU-labeling indices of MCF10AT cells between groups (linear regression)

MCF10AT (n = 6)

27.7 ± 7.2

27.7 ± 7.2

MCF10AT vs MCF10AT + NAF (P = 0.013)

MCF10AT + NAF vs MCF10AT + CAF (P < 0.001)

NAF-1+ MCF10AT (n = 7)

17.1 ± 2.8

14.1 ± 1.4 (n = 20)

  

NAF-2 + MCF10AT (n = 6)

13.8 ± 1.9

   

NAF-3 + MCF10AT (n = 7)

11.4 ± 1.9

   

CAF-1 + MCF10AT (n = 8)

25.9 ± 4.9

25.5 ± 2.8 (n = 22)

MCF10AT vs MCF10AT + CAF (P = 0.935)

 

CAF-2 + MCF10AT (n = 8)

26.6 ± 3.2

   

CAF-3 + MCF10AT (n = 6)

23.5 ± 7.4

   
  1. *Assessed by immunocytochemistry