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Figure 5 | Breast Cancer Research

Figure 5

From: Imaging in situ breast carcinoma (with or without an invasive component) with technetium-99m pentavalent dimercaptosuccinic acid and technetium-99m 2-methoxy isobutyl isonitrile scintimammography

Figure 5

A 4-cm infiltrating lobular carcinoma, grade 3, associated with 6-cm lobular carcinoma in situ (LCIS) of the left breast in a 65-year-old woman (patient 20). (a) Mammography, cranio-caudal projection. Nodular opacity (asterisk) in the inner hemisphere of the breast. (b) Scintimammography, left lateral projection: 99mTc-Sestamibi (99mTc-MIBI) at 10 min and 60 min (upper row, i-ii); 99mTc-(V)DMSA at 10 min and 60 min (bottom row, iii-iv). Focal increased uptake (arrowhead) between upper and lower breast hemisphere, imaged by both radiotracers, corresponding to an invasive tumor. A diffuse patchy 'V'-shaped tracer accumulation (arrows), surrounding the focal activity and extending anterior to it, is revealed with 99mTc-(V)DMSA at 60 min only (iv). It corresponds to LCIS.

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