Figure 3

Staining patterns of lysophosphatidic acid receptor 2 (LPA2) in normal mammary epithelium (upper left) and carcinoma tissues (upper right) of a representative case with high expression, and in another tumour tissue sample with low expression of LPA2 (lower left). Some of the normal epithelial cells in the same specimens, as well as interstitial cells, are slightly stained, but the intensity is significantly weaker than that in carcinoma cells with high expression of LPA2. LPA2 can be detected in the cytoplasm as well as in the cell membrane, but not in the nucleus (lower right).