Figure 12
From: Proteotypic classification of spontaneous and transgenic mammary neoplasms
Type P tumors arise in mice infected by the mouse mammary tumor virus. Myoepithelial differentiation is prominent in ductal areas (a, arrowheads), whereas suprabasal cells have a luminal phenotype and label for K8/18 (b). Clusters and individual suprabasal cells are labeled by antibodies against α-smooth muscle actin (c) and in cells with myoepithelial differentiation (arrowheads). Scale bars, 320 μm (a), 160 μm (b) and 80 μm (c).