Genotypea
| Cases, n (%) | Controls, n (%) | Crude OR (95% CI) | Adjusted OR (95 % CI) |
|---|
G/G (Val/Val) | 869 (69) | 1186 (71) | 1.0b
| 1.0c
|
G/T+T/T(Val/Leu+Leu/Leu) | 383 (31) | 474 (29) | 1.08 (0.92–1.27) | 1.10 (0.93–1.30) |
Premenopausal women | | | | |
G/G(Val/Val) | 68 (65) | 79 (72) | 1.0d
| 1.0e
|
G/T+T/T(Val/Leu+Leu/Leu) | 36 (35) | 31 (28) | 1.35 (0.75–2.41) | 1.21 (0.64–2.28) |
Postmenopausal women | | | | |
G/G(Val/Val) | 745 (69) | 1044 (71) | 1.0f
| 1.0g
|
G/T+T/T(Val/Leu+Leu/Leu) | 330 (31) | 427 (29) | 1.09 (0.92–1.29) | 1.08 (0.91–1.28) |
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aNumbers may vary because of missing genotypes.
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bConditional logistic regression adjusted for the following matching variables: age, menopausal status, postmenopausal hormone use at blood draw, date at blood draw, time at blood draw, and fasting status.
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cConditional logistic regression adjusted for matching variables and age at menarche, age at menopause, age at first birth/parity, Body Mass Index (BMI) at age 18 years, weight gain since age 18 years, benign breast disease, first-degree family history of breast cancer, and duration of postmenopausal hormone use.
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dUnconditional logistic regression adjusted for matching variables listed in footnote b.
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eUnconditional logistic regression adjusted for matching variables in footnote b and other covariates listed in footnote c.
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fUnconditional logistic regression adjusted for the following matching variables: age, menopausal status, postmenopausal use at blood draw, date at blood draw, time at blood draw, and fasting status.
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gUnconditional logistic regression adjusted for matching variables in footnote f and age at menarche, age at first birth/parity, BMI at age 18 years, weight gain since age 18 years, benign breast disease, first-degree family history of breast cancer, and duration of postmenopausal hormone use.
