Skip to main content

Table 2 Comparison of EIs of adsorbed ER onto hydroxylapatite matrix in the absence and presence of protease inhibitors

From: Estrogen receptor of primary breast cancers: evidence for intracellular proteolysis

  EI (%)
  Without protease inhibitors With protease inhibitors
ER 0°C 37°C 0°C 37°C
Cytosol from tumors 69 ± 9 82 ± 16 61 ± 7 59 ± 13
Recombinant hER <10 <10 <10 12 ± 5
MCF-7 cells <10 11 ± 2 13 ± 02 16 ± 4
  1. hER, human full-length ER.