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Table 2 Comparison of EIs of adsorbed ER onto hydroxylapatite matrix in the absence and presence of protease inhibitors

From: Estrogen receptor of primary breast cancers: evidence for intracellular proteolysis

 

EI (%)

 

Without protease inhibitors

With protease inhibitors

ER

0°C

37°C

0°C

37°C

Cytosol from tumors

69 ± 9

82 ± 16

61 ± 7

59 ± 13

Recombinant hER

<10

<10

<10

12 ± 5

MCF-7 cells

<10

11 ± 2

13 ± 02

16 ± 4

  1. hER, human full-length ER.
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Breast Cancer Research

ISSN: 1465-542X

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