Skip to main content

Table 5 Comparison of Her2/neu immunohistochemistry and chromogenic in situ hybridization results with tumor histologic grades

From: Chromogenic in situ hybridization (CISH): a novel alternative in screening archival breast cancer tissue samples for HER-2/neu status

Histologic grade Immunohistochemistry Her2/neu (%)
  Negative (0 and 1+) 2+ 3+
1 4 (5.00) 0 (0.00) 0 (0.00)
2 61 (76.25) 24 (60) 27 (67.50)
3 15 (18.75) 16 (40) 13 (32.50)
Histologic grade Chromogenic in situ hybridization Her2/neu (%)
  No amplification With amplification
   Low High
1 4 (3.92) 0 (0.00) 0 (0.00)
2 75 (73.53) 12 (70.59) 25 (60.98)
3 23 (22.55) 5 (29.41) 16 (39.02)