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Table 5 Comparison of Her2/neu immunohistochemistry and chromogenic in situ hybridization results with tumor histologic grades

From: Chromogenic in situ hybridization (CISH): a novel alternative in screening archival breast cancer tissue samples for HER-2/neu status

Histologic grade

Immunohistochemistry Her2/neu (%)

 

Negative (0 and 1+)

2+

3+

1

4 (5.00)

0 (0.00)

0 (0.00)

2

61 (76.25)

24 (60)

27 (67.50)

3

15 (18.75)

16 (40)

13 (32.50)

Histologic grade

Chromogenic in situ hybridization Her2/neu (%)

 

No amplification

With amplification

  

Low

High

1

4 (3.92)

0 (0.00)

0 (0.00)

2

75 (73.53)

12 (70.59)

25 (60.98)

3

23 (22.55)

5 (29.41)

16 (39.02)