Relationships between subcellular localisation of p14ARF and Hdm2. Scatter plots according to nuclear p14ARF modified Quick-score (MQS) (a, b) and cytoplasmic p14ARF MQS (c, d). p14ARF and Hdm2 staining was analysed as described in the Methods section. (a, b) Distribution of nuclear p14ARF and nuclear Hdm2 (a), and also cytoplasmic Hdm2 (b), showed no significant correlations. (c, d) Distribution of cytoplasmic p14ARF and nuclear Hdm2 (cC), and also cytoplasmic Hdm2 (d), showed significant correlations (P < 0.001, respectively). P values in bold (P < 0.05) indicate significance.