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Table 2 Selected studies of the relationship between histopathology of breast carcinoma and family history

From: The pathology of familial breast cancer: The pre-BRCA1/BRCA2 era - historical perspectives

Author n Study design Main conclusions
Rosen et al [4**] 1024 Breast cancer histology associated with family history (consecutive series of patients treated at Memorial Hospital, New York) Medullary cancer is associated with maternal breast cancer; lobular cancer is associated with breast cancer in a sister
Claus et al [5**] 4071 Breast cancer histology associated with epidemiological factors: part of the Cancer and Steroid Hormone study Medullary cancer is associated with young age; lobular carcinoma in situ is associated with family history