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Table 3 Comparison of density gradient centrifugation systems for the enrichment of disseminated tumor cells in bone marrow (BM)

From: Enrichment methods to detect bone marrow micrometastases in breast carcinoma patients: clinical relevance

After Ficoll

Gradient System

 

HistoPaque

OncoQuick

Tumor cells recovered (%)

34 ± 2

41 ± 8

BM cells remaining (%)

51 ± 5

10 ± 1

BM mononuclear cell enrichment factor

1.5–2.5

9–14.5

Number of slides

51

10