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Table 1 Summary of vascular marker expression

From: Molecular biology of breast cancer metastasis Molecular expression of vascular markers by aggressive breast cancer cells

Human breast Thrombin Endothelin B        
cancer cells receptor receptor TIE-2 CD31 Endoglin Angiopoietin-1 VEGF L32 GAPDH
HUVEC ++ ++* +++ ++ ++ ++ ++ ++ ++
MCF-7 - - - - - - + ++ ++
MB-231 ++ ++ + + - - +++ ++ ++
  1. Comparison of qualitative expression assessment of vascular markers by human breast cancer cells MCF-7 (poorly aggressive), MDA-MB-231 (MB-231; highly aggressive) and HUVECs, as shown in the raw data from the ribonuclease protection assay and differential display analysis in Figure 1. Equal loading of experimental samples was achieved by ribosomal protein L32 (L32) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) control lanes. *Data not shown.