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Table 3 Associations between AIB1 genotypes and breast cancer risk by histologic subtype and receptor status

From: Polymorphic repeat in AIB1 does not alter breast cancer risk

 

No of AIB1 alleles

  
 

with ≤26 repeats

  

Controls/cases

0

1 or 2

OR*

95% Cl

Controls

483

141

  

Cases†

    

   Invasive

295

93

1.13

0.83-1.54

   Ductal

252

79

1.10

0.81-1.53

   Lobular

33

9

1.05

0.48-2.30

   Involved nodes

    

   ≥ 1

83

24

1.07

0.64-1.78

   ≥ 4

30

6

0.72

0.29-1.81

   Receptor status

    

   ER+

189

61

1.16

0.81-1.65

   ER-

46

12

0.94

0.47-1.85

   PR+

142

45

1.14

0.77-1.69

   PR-

86

24

1.03

0.63-1.71

   Tumor size

    

   ≤ 2 cm

207

64

1.13

0.80-1.60

   > 2 cm

74

25

1.21

0.73-2.00

   Degree of differentiation

    

   High or

98

37

1.36

0.89-2.10

   moderate

    

   Poor

55

23

1.54

0.90-2.64

  1. *Unconditional logistic regression adjusted for matching variables: age, menopausal status, postmenopausal hormone use, date of blood sampling, time of blood sampling and fasting status. †Numbers do not add up to total for invasive cancer because of missing data.
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Breast Cancer Research

ISSN: 1465-542X

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