| |
M4 genotypesa
|
wt genotypeb
|
|---|
| |
Cases/controls
|
OR (95% CI)c
|
Cases/controls
|
OR (95% CI)c
|
|---|
|
Active smoking status
| | | | |
|
Never
|
24/16
|
Reference
|
177/190
|
Reference
|
|
Former
|
13/8
|
1.2 (0.4–3.6)
|
123/116
|
1.1 (0.8–1.6)
|
|
Current
|
2/16
|
0.1 (0.0–0.4)
|
78/71
|
1.2 (0.8–1.7)
|
|
Number of cigarettes (pack/day)
| | | | |
|
Never
|
24/16
|
Reference
|
177/190
|
Reference
|
|
≤ 1
|
8/14
|
0.4 (0.1–1.2)
|
128/111
|
1.2 (0.9–1.7)
|
|
> 1
|
7/10
|
0.5 (0.2–1.6)
|
71/75
|
1.0 (0.7–1.5)
|
|
Duration of smoking
| | | | |
|
Never
|
24/16
|
Reference
|
177/190
|
Reference
|
|
≤ 20 years
|
11/12
|
0.6 (0.2–1.8)
|
100/104
|
0.9 (0.6–1.3)
|
|
> 20 years
|
4/12
|
0.2 (0.1–0.9)
|
101/83
|
1.5 (1.0–2.1)
|
|
Former smokers: time since cessation of smoking
| | | | |
|
Never
|
24/16
|
Reference
|
177/190
|
Reference
|
|
< 10 years
|
6/3
|
1.4 (0.3–6.6)
|
67/48
|
1.4 (0.9–2.2)
|
|
≥ 10 years
|
7/5
|
1.0 (0.3–3.8)
|
56/68
|
0.9 (0.6–1.4)
|
|
Age started smoking
| | | | |
|
Never
|
24/16
|
Reference
|
177/190
|
Reference
|
|
< 18 years
|
7/9
|
0.5 (0.2–1.8)
|
71/66
|
1.1 (0.7–1.6)
|
|
≥ 18 years
|
8/15
|
0.4 (0.1–1.1)
|
130/121
|
1.2 (0.9–1.7)
|
- CI, confidence interval; wt, wild type. a M4/M4 and M4/wt genotypes. b wt/wt genotype. cAdjusted for age, race, and sampling fractions.
