| |
M3 genotypesa
|
wt genotypeb
|
|---|
| |
Cases/controls
|
OR (95% CI)c
|
Cases/controls
|
OR (95% CI)c
|
|---|
|
Active smoking status
| | | | |
|
Never
|
24/32
|
Referent
|
124/134
|
Reference
|
|
Former
|
16/11
|
1.9 (0.7–4.8)
|
58/42
|
1.7 (1.1–2.7)
|
|
Current
|
7/10
|
0.9 (0.7–2.8)
|
36/51
|
0.8 (0.5–1.3)
|
|
Number of cigarettes (pack/day)
| | | | |
|
Never
|
24/32
|
Referent
|
124/134
|
Reference
|
|
≤ 1
|
18/16
|
1.5 (0.6–3.5)
|
79/82
|
1.2 (0.8–1.7)
|
|
> 1
|
5/5
|
1.2 (0.3–4.7)
|
14/11
|
1.6 (0.7–3.8)
|
|
Duration of smoking
| | | | |
|
Never
|
24/32
|
Referent
|
124/134
|
Reference
|
|
≤ 20 years
|
8/13
|
0.8 (0.3–2.2)
|
54/55
|
1.2 (0.7–1.8)
|
|
> 20 years
|
15/8
|
2.5 (0.9–7.1)
|
39/37
|
1.3 (0.8–2.2)
|
|
Former smokers: time since cessation of smoking
| | | | |
|
Never
|
24/32
|
Referent
|
124/134
|
Reference
|
|
< 10 years
|
13/4
|
4.2 (1.2–14.6)
|
32/13
|
3.1 (1.5–6.1)
|
|
≥ 10 years
|
3/7
|
0.5 (0.1–2.3)
|
26/29
|
1.1 (0.6–2.0)
|
|
Age started smoking
| | | | |
|
Never
|
24/32
|
Referent
|
124/134
|
Reference
|
|
< 18 years
|
12/6
|
2.4 (0.8–7.5)
|
33/29
|
1.3 (0.7–2.3)
|
|
≥ 18 years
|
11/15
|
1.0 (0.4–2.5)
|
61/64
|
1.2 (0.8–1.8)
|
- CI, confidence interval; wt, wild type. a M3/M3 and M3/wt genotypes. b wt/wt genotype. cAdjusted for age and sampling fractions.
