Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 5 Odds ratios (ORs) for breast cancer and smoking in relation to the CYP1A1 genotype at the M2 locus (white women only)

From: Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women

  M2 genotypesa wt genotypeb
  Cases/controls OR (95% CI)c Cases/controls OR (95% CI)c
Active smoking status     
   Never 15/15 Referent 186/191 Referent
   Former 11/18 0.5 (0.2–1.6) 125/106 1.2 (0.9–1.7)
   Current 6/6 0.9 (0.2–3.5) 74/81 0.9 (0.6–1.4)
Number of cigarettes (pack/day)     
   Never 15/15 Referent 186/191 Referent
   ≤ 1 10/11 0.8 (0.3–2.6) 126/114 1.1 (0.8–1.6)
   > 1 7/13 0.5 (0.1–1.5) 71/72 1.0 (0.7–1.5)
Duration of smoking     
   Never 15/15 Referent 186/191 Referent
   ≤ 20 years 6/16 0.3 (0.1–1.0) 105/100 1.0 (0.7–1.4)
   > 20 years 11/8 1.4 (0.4–4.8) 94/87 1.3 (0.9–1.8)
Former smokers: time since cessation of smoking     
   Never 15/15 Referent 186/191 Referent
   < 10 years 10/7 1.3 (0.4–4.3) 63/44 1.4 (0.9–2.2)
   ≥ 10 years 1/11 0.1 (0.0–0.8) 62/62 1.1 (0.7–1.7)
Age started smoking     
   Never 15/15 Referent 186/191 Referent
   < 18 years 6/8 0.5 (0.1–2.0) 72/67 1.0 (0.7–1.6)
   ≥ 18 years 11/16 0.7 (0.2–2.0) 127/120 1.1 (0.8–1.6)
  1. CI, confidence interval; wt, wild type. a M2/M2 and M2/wt genotypes. b wt/wt genotype. cAdjusted for age and sampling fractions.