| |
M2 genotypesa
|
wt genotypeb
|
|---|
| |
Cases/controls
|
OR (95% CI)c
|
Cases/controls
|
OR (95% CI)c
|
|---|
|
Active smoking status
| | | | |
|
Never
|
15/15
|
Referent
|
186/191
|
Referent
|
|
Former
|
11/18
|
0.5 (0.2–1.6)
|
125/106
|
1.2 (0.9–1.7)
|
|
Current
|
6/6
|
0.9 (0.2–3.5)
|
74/81
|
0.9 (0.6–1.4)
|
|
Number of cigarettes (pack/day)
| | | | |
|
Never
|
15/15
|
Referent
|
186/191
|
Referent
|
|
≤ 1
|
10/11
|
0.8 (0.3–2.6)
|
126/114
|
1.1 (0.8–1.6)
|
|
> 1
|
7/13
|
0.5 (0.1–1.5)
|
71/72
|
1.0 (0.7–1.5)
|
|
Duration of smoking
| | | | |
|
Never
|
15/15
|
Referent
|
186/191
|
Referent
|
|
≤ 20 years
|
6/16
|
0.3 (0.1–1.0)
|
105/100
|
1.0 (0.7–1.4)
|
|
> 20 years
|
11/8
|
1.4 (0.4–4.8)
|
94/87
|
1.3 (0.9–1.8)
|
|
Former smokers: time since cessation of smoking
| | | | |
|
Never
|
15/15
|
Referent
|
186/191
|
Referent
|
|
< 10 years
|
10/7
|
1.3 (0.4–4.3)
|
63/44
|
1.4 (0.9–2.2)
|
|
≥ 10 years
|
1/11
|
0.1 (0.0–0.8)
|
62/62
|
1.1 (0.7–1.7)
|
|
Age started smoking
| | | | |
|
Never
|
15/15
|
Referent
|
186/191
|
Referent
|
|
< 18 years
|
6/8
|
0.5 (0.1–2.0)
|
72/67
|
1.0 (0.7–1.6)
|
|
≥ 18 years
|
11/16
|
0.7 (0.2–2.0)
|
127/120
|
1.1 (0.8–1.6)
|
- CI, confidence interval; wt, wild type. a M2/M2 and M2/wt genotypes. b wt/wt genotype. cAdjusted for age and sampling fractions.
