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Table 1 Genotype frequencies for CYP1A1 among African-American and white participants in the Carolina Breast Cancer Study (1993–1996)
| African-Americans | Whites | |||
|---|---|---|---|---|
| Cases (n = 271) | Controls (n = 285) | Cases (n = 417) | Controls (n = 417) | |
| M1 locus | ||||
| wt/wt | 155 (59%) | 165 (59%) | 327 (79%) | 325 (78%) |
| wt/M1 | 93 (35%) | 102 (36%) | 78 (19%) | 83 (20%) |
| M1/M1 | 17 (6%) | 13 (5%) | 8 (2%) | 7 (2%) |
| Missing | 6 | 5 | 4 | 2 |
| Chi-square test, P* | 0.65 | 0.89 | ||
| M2 locus | ||||
| wt/wt | 259 (96%) | 274 (96%) | 385 (92%) | 378 (90%) |
| wt/M2 | 12 (4%) | 11 (4%) | 29 (7%) | 37 (9%) |
| M2/M2 | 0 | 0 | 3 (1%) | 2 (1%) |
| Missing | 0 | 0 | 0 | 0 |
| Fisher's exact test, P* | 0.83 | 0.61 | ||
| M3 locus | ||||
| wt/wt | 218 (82%) | 227 (81%) | 412 (99.8%) | 413 (99.6%) |
| wt/M3 | 47 (18%) | 47 (17%) | 1 (0.2%) | 1 (0.2%) |
| M3/M3 | 0 | 6 (2%) | 0 | 1 (0.2%) |
| Missing | 6 | 5 | 4 | 2 |
| Fisher's exact test, P* | 0.06 | 0.99 | ||
| M4 locus | ||||
| wt/wt | 267 (98.5%) | 278 (97.5%) | 378 (90.7%) | 377 (90%) |
| wt/M4 | 3 (1.1%) | 7 (2.5%) | 38 (9.1%) | 40 (10%) |
| M4/M4 | 1 (0.4%) | 0 | 1 (0.2%) | 0 |
| Missing | 0 | 0 | 0 | 0 |
| Fisher's exact test, P* | 0.28 | 0.91 | ||
