Skip to main content

Table 4 Distribution of ESR1 four-locus haplotype frequencies as estimated through expectation-maximisation algorithms

From: Oestrogen receptor α gene haplotype and postmenopausal breast cancer risk: a case control study

Locus

Proportion

c.454-397C→T

c.454-351A→G

c.729C→T

c.975C→G

Controls (n = 1511)

Ductal cases (n = 1148)

Lobular cases (n = 184)

T

A

C

C

0.369

0.404

0.373

C

G

C

C

0.285

0.267

0.276

C

A

C

C

0.114

0.117

0.125

T

A

C

G

0.123

0.117

0.123

C

G

C

G

0.058

0.049

0.076

T

A

T

G

0.032

0.027

0.021

Proportion accounted for by the above most common haplotypes:

0.981

0.981

0.994